10 Best Stains Removers to Tackle Tough Spots

What are the best stain removers for tackling tough spots?
We’re sharing a curated list of top-rated stain removers, complete with engaging stories from real users who rave about how these products revived their favorite garments.

Tired of stubborn stains ruining your clothes? Finding the perfect stain remover can be a real challenge. Don’t worry, we’ve got you covered with the best stain removers available!

We’ve gathered the top products to help you. Real users love these stain-fighting heroes. Get ready to say goodbye to stains and hello to fresh, clean clothes!

List of Top 10 Stains Removers

Image Title Best For Price
Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains - Prewash Spray 22oz Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains – Prewash Spray 22oz

Shout Active Enzyme Spray is perfect for busy families and college students who need stains gone quickly. Great for anyone with kids and everyday messes.

Miss Mouth's Messy Eater Stain Treater Spray - 4oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric Miss Mouth’s Messy Eater Stain Treater Spray – 4oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

This spray is perfect for busy families with babies and toddlers who deal with messes from food, drinks, and daily spills. It’s also great for anyone who cleans clothes, upholstery, or carpets and wants fast, safe stain relief.

Shout Advanced Stain Remover Gel for Clothes Laundry, Ultra Concentrated Gel with Built-in Scrubber Brush for Deep Set-In stains, 8.7oz Shout Advanced Stain Remover Gel for Clothes Laundry, Ultra Concentrated Gel with Built-in Scrubber Brush for Deep Set-In stains, 8.7oz

This Shout Advanced Stain Remover Gel is perfect for everyone. It is for anyone who wants to remove tough stains from their clothes easily.

OxiClean Max Force Laundry Stain Remover Gel Stick, 6.2 fl oz OxiClean Max Force Laundry Stain Remover Gel Stick, 6.2 fl oz

Got tough stains? OxiClean Max Force Gel Stick is your new best friend. It’s perfect for busy people who want to remove stains easily and wash later.

Miss Mouth's Messy Eater Stain Treater Spray - 4oz 2 Pack Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric Miss Mouth’s Messy Eater Stain Treater Spray – 4oz 2 Pack Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

This stain treater spray is perfect for parents of newborns and babies who deal with messy feeds, spills, and stains on clothes every day. It’s also great for toddlers, families with young kids, or anyone needing a quick fix for tough marks on fabric.

Miss Mouth's Messy Eater Stain Treater Spray - 16oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric Miss Mouth’s Messy Eater Stain Treater Spray – 16oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

This stain spray is perfect for busy parents and caregivers who clean up after kids. It tackles fruit juice, baby food, formula, ketchup and other spills fast and safely.

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains – 22oz Spray

This gel is perfect for busy moms and dads who need to quick-fix kid stains on clothes.
It also works great for anyone dealing with tough dirt or spills from meals.

Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains - Prewash Refill 60oz (1.7L) Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains – Prewash Refill 60oz (1.7L)

Busy parents dealing with kids’ messes, active folks tackling dirt and stains, or anyone who wants quick fixes for food, drinks, and grass spots on clothes—this Shout spray is your easy helper for clean fabrics. Use it on whites or colors before washing, and say goodbye to stubborn marks without fuss.

Tide Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in Purses & Bags, 3 Count (Pack of 1) Tide Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in Purses & Bags, 3 Count (Pack of 1)

This Tide Stain Remover is perfect for anyone who wants to stay clean on the go. It’s great for people who want to remove stains from clothes quickly and easily.

Seventh Generation Laundry Stain Remover, Free & Clear, Unscented, 16 Fl Oz Seventh Generation Laundry Stain Remover, Free & Clear, Unscented, 16 Fl Oz

This stain remover is perfect for busy parents who want an easy way to clean tough messes on clothes. It works with plant-based power and lets you spray on stains and wash later, so laundry is simple and quick.

Detailed Reviews

Discover the Best Stains Removers with our top picks that always get results. We picked these based on expert analysis and customer feedback for total trust. Each one shines in features, performance, and value to match what you need. Dive into this guide to find your perfect stain-fighting hero today.

1. Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains – Prewash Spray 22oz

Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains - Prewash Spray 22oz

Tackle tough stains with Shout Active Enzyme Laundry Stain Remover Spray. This 22oz bottle packs a triple-acting formula that clings, penetrates, and lifts. It fights 100+ everyday stains from food, drinks, and dirt.

The spray is 50x more concentrated than regular in-wash powder. Just spray, rub, and wash—it works on whites and colors in any temperature.

Use it right away or wait up to a week to clean. Grab yours today for spotless clothes every time.

Pros Cons
  • Powerful stain removal from a spray
  • Clings to fabric for direct stain treatment
  • Works on all temps and washers
  • Treats 100+ stains with enzyme power
  • Easy prewash spray that works fast
  • Strong chemical smell might linger after washing.
  • Needs washing soon to avoid stain marks.
  • Spray bottle can be messy to use.

Perfect For:

Shout Active Enzyme Spray is perfect for busy families and college students who need stains gone quickly. Great for anyone with kids and everyday messes.

Ready to Purchase?

2. Miss Mouth’s Messy Eater Stain Treater Spray – 4oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth's Messy Eater Stain Treater Spray - 4oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth’s Messy Eater Stain Treater Spray is a 4oz stain remover. It tackles food, grease, and coffee stains on laundry, underwear, and fabric. This newborn and baby essential works fast and safe.

Our spray is EPA Safer Choice certified for family peace of mind. It removes fresh and set-in stains from baby food, juice, ketchup, and more with ease.

Pros Cons
  • Fast-acting formula tackles tough stains quickly.
  • Safe for your family with EPA Safer Choice certification.
  • Works wonders on various stains from baby food to blood.
  • Easy to use: spray, rub, and wash—it’s that simple!
  • May not remove very old stains.
  • Might need more than one spray for tough spots.
  • Not for all fabric types.

Perfect For:

This spray is perfect for busy families with babies and toddlers who deal with messes from food, drinks, and daily spills. It’s also great for anyone who cleans clothes, upholstery, or carpets and wants fast, safe stain relief.

Ready to Purchase?

3. Shout Advanced Stain Remover Gel for Clothes Laundry, Ultra Concentrated Gel with Built-in Scrubber Brush for Deep Set-In stains, 8.7oz

Shout Advanced Stain Remover Gel for Clothes Laundry, Ultra Concentrated Gel with Built-in Scrubber Brush for Deep Set-In stains, 8.7oz

Say goodbye to tough stains with Shout Advanced Stain Remover Gel! This ultra-concentrated gel is designed to tackle even the most stubborn marks on your clothes. It comes with a built-in scrubber brush for easy stain removal.

This stain remover is simple to use. Just squeeze, rub, and wash. It works on many types of fabrics.

Pros Cons
  • Powerful gel smashes even the toughest, set-in stains!
  • Built-in brush gets deep into fibers for ultimate clean.
  • Gentle on fabrics, yet relentless on dirt and grime.
  • Easy to use: Squeeze, rub, wash, and stains are gone!
  • Works on all colors and whites, in any water temp!
  • Small bottle may run out fast.
  • Built-in brush may snag fabrics.
  • Some stains need multiple applications.

Perfect For:

This Shout Advanced Stain Remover Gel is perfect for everyone. It is for anyone who wants to remove tough stains from their clothes easily.

Ready to Purchase?

4. OxiClean Max Force Laundry Stain Remover Gel Stick, 6.2 fl oz

OxiClean Max Force Laundry Stain Remover Gel Stick, 6.2 fl oz

Here it is: OxiClean Max Force Gel Stick is your stain solution. It fights tough, dried-in messes. This little stick is small but mighty!

This gel lets you pretreat clothing at your own speed. Wash up to seven days later! That’s right!

This stuff is amazing on all sorts of messes! It even works on baby clothes! Get OxiClean Max Force now.

Pros Cons
  • Zaps stubborn and dried-in stains quickly.
  • Pretreat now, wash later up to a week.
  • Fights tough spots like grease, grass, and ink.
  • Safe on all machine-washable fabrics, including kids’ clothes.
  • Simple rub-on gel for easy cleaning.
  • Small size runs out fast for big loads.
  • Wait time needed; no instant fix.
  • Not great on tough, set-in stains.

Perfect For:

Got tough stains? OxiClean Max Force Gel Stick is your new best friend. It’s perfect for busy people who want to remove stains easily and wash later.

Ready to Purchase?

5. Miss Mouth’s Messy Eater Stain Treater Spray – 4oz 2 Pack Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth's Messy Eater Stain Treater Spray - 4oz 2 Pack Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth’s Messy Eater stain spray is a fast-acting cleaner that works on clothes, upholstery, and carpets. It tackles dirty messes from baby food, fruit juice, and even blood with ease.
This spray gets the EPA Safer Choice seal, so you know it’s safe for your family. It’s great for both fresh stains and old ones that have set in over time.
Use it by spraying on the spot and washing as usual. It works on laundry, underwear, and fabrics without dry cleaning. Repeat if needed for total clean.

Pros Cons
  • Powerfully removes tough stains fast.
  • Safely cleans for babies and families.
  • Easily handles baby food and juice.
  • Simply spray and wash away messes.
  • Effectively works on fresh or old spots.
  • Might need repeat applications for some stains.
  • Dampening needed; extra step before spraying.
  • Only 4oz, may run out fast with lots of spills!

Perfect For:

This stain treater spray is perfect for parents of newborns and babies who deal with messy feeds, spills, and stains on clothes every day. It’s also great for toddlers, families with young kids, or anyone needing a quick fix for tough marks on fabric.

Ready to Purchase?

6. Miss Mouth’s Messy Eater Stain Treater Spray – 16oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth's Messy Eater Stain Treater Spray - 16oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth’s Messy Eater Stain Treater Spray is a fast stain remover. It works on clothes, upholstery, and carpets.

It is SAFER CHOICE CERTIFIED, safe for babies and families. No dry cleaning is needed.

It works on fresh and set stains. Spray it on, rub a little, then wash. If it stays, repeat.

Pros Cons
  • Powerful and fast stain removal for clothes.
  • Safer Choice certified for safer cleaning.
  • Works on stains for fresh and set-in messes.
  • Baby-safe formula, gentle on fabrics.
  • Easy-to-use spray, rub, wash.
  • Repeat spray needed for stubborn stains
  • Small 16oz bottle may run out fast
  • May leave fabrics damp briefly

Perfect For:

This stain spray is perfect for busy parents and caregivers who clean up after kids. It tackles fruit juice, baby food, formula, ketchup and other spills fast and safely.

Ready to Purchase?

7. Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains – 22oz Spray

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray

Tired of stubborn stains ruining your favorite clothes? Get ready for Shout Advanced Laundry Stain Remover Gel! This powerful gel is designed to tackle even the toughest, dried-in messes.

This gel is truly amazing. It is quick and easy to use. Just spray, rub, wash, and done!

With 70% more stain-fighting power, you can trust Shout to get the job done. Say goodbye to stains and hello to fresh, clean clothes!

Pros Cons
  • Toughest stains are gone with our best Shout formula!
  • Heavy duty gel tackles food, makeup, and more.
  • Easy to use: Just spray, rub, wash, and done!
  • Works on all machine-washable fabrics and temperatures.
  • Made with recycled plastic: Good for your clothes and planet!
  • Strong chemical smell lingers
  • Pricey for the bottle size
  • Messy gel can drip easily

Perfect For:

This gel is perfect for busy moms and dads who need to quick-fix kid stains on clothes.
It also works great for anyone dealing with tough dirt or spills from meals.

Ready to Purchase?

8. Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains – Prewash Refill 60oz (1.7L)

Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains - Prewash Refill 60oz (1.7L)

Shout Active Enzyme tackles tough stains on clothes. It fights everyday messes like food, drinks, makeup, grass, and dirt. The triple-acting formula clings, soaks in, and pulls out stains fast.

Use it on all fabrics that you can wash in a machine. Spray it, rub lightly, and wash later—even after a week.

Pros Cons
  • Powerful stain lift in one spray.
  • Clings, penetrates, lifts tough stains.
  • 50x concentrated for fast action.
  • Works in all temps and washers.
  • Prewash spray saves time and effort.
  • Pricey per load.
  • Only for machine-washable fabrics.
  • Requires immediate use for best results.

Perfect For:

Busy parents dealing with kids’ messes, active folks tackling dirt and stains, or anyone who wants quick fixes for food, drinks, and grass spots on clothes—this Shout spray is your easy helper for clean fabrics. Use it on whites or colors before washing, and say goodbye to stubborn marks without fuss.

Ready to Purchase?

9. Tide Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in Purses & Bags, 3 Count (Pack of 1)

Tide Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in Purses & Bags, 3 Count (Pack of 1)

Keep your clothes looking their best with the Tide Stain Remover Pen! This handy pen is perfect for tackling fresh stains when you’re on the go.

This pocket-sized pen is easy to carry. It’s gentle on clothes but tough on stains. It works on many food and drink spills.

Using the pen is simple. Blot up any excess residue. Then, press and rub the stain. Enjoy clean clothes!

Pros Cons
  • Removes stains quickly and easily.
  • Portable size fits in any bag.
  • Gentle on clothes, tough on stains.
  • Works on many food and drink stains.
  • Simple 3-step stain removal process.
  • Not effective on set-in stains.
  • Tiny tip may miss stubborn spots.
  • Not for large stains or heavy messes.

Perfect For:

This Tide Stain Remover is perfect for anyone who wants to stay clean on the go. It’s great for people who want to remove stains from clothes quickly and easily.

Ready to Purchase?

10. Seventh Generation Laundry Stain Remover, Free & Clear, Unscented, 16 Fl Oz

Seventh Generation Laundry Stain Remover, Free & Clear, Unscented, 16 Fl Oz

Seventh Generation Laundry Stain Remover fights stains like a champ. It uses 97% plant-based ingredients for a clean lift.

This remover has a quadruple-enzyme formula that breaks down tough dirt. Spray it now and wash your clothes later—pure ease.

Stains vanish fast. No dyes or fake scents here. We list all ingredients right on the box.

Pros Cons
  • Eco-friendly cleaner with 97% plant-based ingredients.
  • Removes tough stains using quadruple enzymes.
  • Spray now, wash later for easy convenience.
  • Free of dyes and artificial fragrances.
  • Lists all ingredients right on the package.
  • Unscented formula won’t add a fresh smell.
  • 16 oz size may run out too fast.
  • Plant-derived ingredients might be more pricey.

Perfect For:

This stain remover is perfect for busy parents who want an easy way to clean tough messes on clothes. It works with plant-based power and lets you spray on stains and wash later, so laundry is simple and quick.

Ready to Purchase?

Buying Guide

Picking the right stain remover saves time and keeps clothes fresh. Users pick based on ease and power for daily messes.
Real users love how Shout Active Enzyme Spray wipes out berry juice spills on kids’ shirts right before laundry. One mom shared she sprayed and rubbed on set-in tomato sauce stains, seeing clean results without scrubbing hard.
Product Type: Choose sprays for quick treats on fresh spots. Gels stick to deep stains for heavy lifting. Pens fit pockets for travel fixes without mess.
Effectiveness on Stains: Look for formulas that handle food, drink, and dirt messes. Enzymes break down proteins in tough spots like blood or grass. Check for claims on 100-plus stain types to cover everyday life.
Safety and Ingredients: Pick options safe for babies and fabrics. EPA-certified or plant-based choices avoid harsh chemicals. Unscented versions suit sensitive noses without dyes.
Ease of Use: Go for sprays you just apply and wash. Built-in brushes on gels add convenience for rubbing. Portable pens work on the go without extra steps.
Quantity and Size: Larger bottles last longer for families. Small packs travel light for trips. Refills cut costs over single-use sizes.
Pre-Wash Delay Time: Select ones you can apply now and wash later. Options waiting up to a week fit busy schedules. Instant pens solve spills without planning.
Price and Value: Compare costs per ounce for big savings. Concentrated formulas last more, giving better bang for bucks. Brands with user praise often pay off in real spotless clothes.