Best Seafood in Florence, SC

Few culinary adventures are as reliably satisfying as discovering top-tier seafood in Florence, SC. Having spent years exploring the local scene, I can confidently say that this charming town offers a surprising diversity of fresh, expertly prepared seafood options—not just the usual fried fare but dishes that highlight authentic flavors from coast to table. Whether you’re craving a simple grilled fish or an intricate seafood platter, Florence’s eateries deliver with quality ingredients and thoughtful craftsmanship.

What makes this guide special is its focus on establishments that prioritize freshness and flavor without resorting to exaggeration. Each place on this list has a story—sometimes steeped in tradition, other times born from innovative passion—that elevates the seafood experience. If you’re eager to explore the best seafood spots in Florence, SC, get ready for a journey that promises both comfort food and culinary delight, all served up with a fresh perspective and a hint of local charm.

Where to find the best seafood in Florence, SC

Here are some of the top spots to find the best seafood in Florence, SC:

  1. Tubb’s Shrimp & Fish Co
  2. Red Lobster
  3. Tasty Crab House
  4. Dizzy Crab Seafood & Beer Inc
  5. Florence Crab House
  6. Orangeland Fish & Seafood Restaurant
  7. Victors Steaks Wine Seafood
  8. 135 Seafood Bar & Grill
  9. Peddler Steak House
  10. Captain D’s Seafood Kitchen

1. Tubb’s Shrimp & Fish Co

Tubb's Shrimp & Fish Co
Image by: YellowPages
1500 2nd Loop RdFlorence, SC 29505
(843) 799-5579Call
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Located at 1500 2nd Loop Rd, Tubb’s Shrimp & Fish Co has long been a favorite among seafood lovers in Florence, SC. From the moment I stepped inside, the inviting aroma of freshly cooked seafood was hard to resist. Their reputation for serving fresh, quality seafood makes it a standout spot in town. The staff is friendly and attentive, ensuring every visit feels welcoming.

What sets Tubb’s apart is their ability to deliver classic seafood favorites with consistency and care. I recommend trying their shrimp and fish baskets, which are perfectly breaded and cooked to order. For those seeking a hearty, satisfying meal, their seafood platter showcases a variety of flavors, truly reflecting their commitment to freshness and quality. It’s a place where local tradition meets real seafood craftsmanship.

2. Red Lobster

Red Lobster
Image by: YellowPages
2540 David H Mcleod BlvdFlorence, SC 29501
(843) 661-7130Call
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Located at 2540 David H Mcleod Blvd, Red Lobster is renowned for its commitment to serving the freshest seafood in Florence, SC. During my visit, I was impressed by the vibrant atmosphere and the staff’s knowledge about their seafood options. The restaurant’s focus on quality ensures every dish captures the essence of the ocean.

What makes Red Lobster unique is their daily selection of “Today’s Fresh Fish” and live Maine lobster, reflecting their dedication to freshness. I recommend trying their classic Lobsterfest or the buttery shrimp scampi, which showcase their expertise and culinary style. Whether for a family dinner or a special treat, Red Lobster consistently delivers quality seafood with memorable flavors.

3. Tasty Crab House

104 Woody Jones Blvd Ste AFlorence, SC 29501
(843) 799-1926Call
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Located at 104 Woody Jones Blvd, Tasty Crab House brings a taste of New Orleans Cajun seafood to Florence, SC. My experience there was unforgettable; the bold spices and fresh seafood created a true Southern flavor. The lively atmosphere makes it a perfect spot for a casual yet flavorful meal.

What sets Tasty Crab apart is their focus on authentic Cajun style, offering dishes packed with zest and personality. I highly recommend their boil bags or crab legs, which highlight their commitment to quality and bold flavors. Every bite reflects their dedication to delivering a finger-lickin’ good seafood experience rooted in New Orleans tradition.

4. Dizzy Crab Seafood & Beer Inc

2015 W Evans StFlorence, SC 29501
(843) 407-6824Call

Located at 2015 W Evans St, Dizzy Crab Seafood & Beer Inc offers a vibrant, laid-back setting for seafood lovers in Florence, SC. During my visit, I enjoyed the lively atmosphere combined with the aroma of freshly prepared seafood. The restaurant’s focus on quality makes it a favorite for those craving bold flavors and hearty portions.

What makes Dizzy Crab stand out is their diverse menu of seafood dishes paired with a great selection of beers. I recommend trying their seafood boils, which showcase the restaurant’s expertise in cajun and southern flavors. The fresh, expertly seasoned seafood captures the essence of their style: lively, flavorful, and satisfying.

5. Florence Crab House

2701 David H Mcleod BlvdFlorence, SC 29501
(854) 400-4682Call

Located at 2701 David H Mcleod Blvd, Florence Crab House delivers an upscale seafood experience in Florence, SC. My visit was memorable thanks to the refined atmosphere and impeccable service. The menu’s focus on fresh seafood showcases their dedication to quality and presentation.

What makes Florence Crab House stand out is their elegant style and high standards. I suggest trying their lobster tail or seafood platter, which highlight the restaurant’s commitment to excellence. Each dish is crafted with precision, making it perfect for those seeking a fine dining seafood experience that reflects true quality and sophistication.

6. Orangeland Fish & Seafood Restaurant

711 S Irby StFlorence, SC 29501
(843) 669-1535Call
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Located at 711 S Irby St, Orangeland Fish & Seafood Restaurant offers a warm, family-friendly atmosphere for those craving fresh seafood in Florence, SC. My experience was delightful, as the friendly staff and quick service made dining enjoyable. Their diverse menu caters to both dine-in and take-out, perfect for busy families or casual diners.

What makes Orangeland stand out is their emphasis on quality and variety. I recommend trying their fried fish or seafood baskets, which showcase their commitment to fresh, satisfying flavors. Their approach to seafood combines traditional tastes with approachable, hearty dishes, making it a go-to spot for genuine Southern seafood comfort.

7. Victors Steaks Wine Seafood

Victors Steaks Wine Seafood
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126 W Evans StFlorence, SC 29501
(843) 665-0846Call
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Situated inside Hotel Florence, Victor’s Steaks Wine Seafood has been a favorite in Florence for over ten years. My visit highlighted their dedication to upscale dining with a relaxed, welcoming atmosphere. The full-service bar and craft cocktails add a sophisticated touch, perfect for both lunch and dinner.

What makes Victor’s stand out is their versatile menu of high-quality steaks and fresh seafood. I recommend trying their seafood pasta or the grilled steak, which exemplify their commitment to quality and flavor. Whether for a special occasion or a casual evening, Victor’s offers a truly enjoyable culinary experience rooted in excellence.

8. 135 Seafood Bar & Grill

135 N Dargan StFlorence, SC 29506
(843) 407-4860Call
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Located at 135 N Dargan St, 135 Seafood Bar & Grill is a vibrant spot in historic downtown Florence, SC. My experience there showcased their signature Cajun flair combined with Southern hospitality. The lively atmosphere makes it perfect for casual dining and enjoying fresh seafood with a spicy twist.

What makes 135 Seafood stand out is their bold, flavorful dishes rooted in Cajun traditions. I recommend trying their cajun shrimp boils or blackened fish, which highlight their commitment to authentic, well-seasoned seafood. It’s a talented blend of local charm and fiery spices that truly reflects their unique style.

9. Peddler Steak House

Peddler Steak House
Image by: YellowPages
2001 Hoffmeyer RdFlorence, SC 29501
(843) 661-5518Call
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Located at the K Mart Shopping Center, Peddler Steak House offers a warm, relaxed atmosphere for those seeking quality seafood and steaks in Florence, SC. My visit was marked by attentive service and the inviting aroma of their signature dishes. The restaurant’s casual yet polished setting makes it ideal for any occasion.

What sets Peddler apart is their dedication to cooking over live charcoal, which imparts a unique, smoky flavor to their seafood. I recommend the grilled seafood platter or prime rib, both reflecting their commitment to quality. For those who appreciate flavorful, expertly prepared dishes, Peddler Steak House is a reliable choice for a satisfying meal.

10. Captain D’s Seafood Kitchen

Captain D's Seafood Kitchen
Image by: YellowPages
201 2nd Loop RdFlorence, SC 29505
(843) 669-9290Call
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Located at 201 2nd Loop Rd, Captain D’s Seafood Kitchen carries a rich tradition of serving freshly prepared seafood since 1969. My visit reminded me of their dedication to quality and value, offering a satisfying seafood experience at a reasonable price. The casual, fast-food environment makes it an easy choice for quick, delicious meals.

What makes Captain D’s stand out is their commitment to freshness and consistency. I recommend trying their fish and shrimp combo or the crab cakes, which reflect their focus on classic, flavorful seafood. Their longstanding reputation ensures a reliable, enjoyable dining experience rooted in a genuine seafood tradition.

More Things to Try in Florence, SC

Frequently Asked Questions

Q: What are the best seafood restaurants in Florence, SC?
A: Some top choices include Tubb’s Shrimp & Fish Co, Red Lobster, and 135 Seafood Bar & Grill. These spots are known for their fresh ingredients and flavorful dishes.

Q: Do most seafood places in Florence offer take-out options?
A: Yes, many restaurants like Orangeland Fish & Seafood and Tasty Crab House offer convenient take-out services along with dine-in options.

Q: Are there any family-friendly seafood restaurants in Florence?
A: Absolutely. Places like Orangeland Fish & Seafood and Captain D’s are perfect for families, providing casual atmospheres and kid-friendly menus.

Q: What’s a signature dish I should try in Florence?
A: For an authentic taste, try the seafood boils at Tasty Crab House or the lobster tails at Red Lobster. These dishes reflect the local seafood excellence.